![]() Older people who don’t get enough vitamin B12 may be at higher risk for anemia and infections. It may cause nerve damage, and studies show low vitamin B12 levels may be a risk factor for problems in cognitive function such as dementia and psychosis. Left untreated, a vitamin B12 deficiency may lead to decreased motor function, including balance problems, tremors, an increased risk of falling, and numbness or tingling in your extremities.Ĭhronic vitamin B12 deficiency in blood levels can dramatically affect the brain and nervous system. Chronic deficiency may result in weight loss, loss of appetite, and digestive issues. These may include confusion, depression, difficulty recalling or remembering information, and tiredness. When you don’t get enough vitamin B12, you may experience deficiency symptoms. Additional research indicates low levels of vitamin B12 may increase the risk of macular degeneration. Studies show low vitamin B12 levels have been linked with osteoporosis. Vitamin B12 may also play a part in bone and vision health. That’s why you may feel fatigued or dizzy when you have a deficiency. Vitamin B12 helps to create and reproduce blood cells and is also involved in producing energy. This amino acid has been linked to cognitive decline in Alzheimer’s and Parkinson’s disease. Vitamin B12 helps to metabolize an amino acid known as homocysteine. Vitamin B12 is particularly important because it plays a role in brain function, metabolism, nerve cells, and blood health. ![]() It is only contraindicated in patients with inability to take oral medication or who present vomiting or diarrhea.It’s no secret that getting your vitamins and nutrients is key to staying healthy. The oral treatment avoids the complications inherent to the injection and also relative contraindications, such as anticoagulation. Adverse effects to overdosage of vitamin B12 have not been reported. Thus, if the daily needs of B12 are approximately 2 μg, administering oral supplements at high doses (1-2 mg) once a day can achieve a sufficient amount to ensure the values and filling of the tissue stores through passive intestinal absorption. Several studies have shown that the small percentage (1-2%) of vitamin that is passively absorbed in the intestine could be sufficient to achieve, with high doses of vitamin B12, adequate concentrations in the body, even in cases of absence of IF by pernicious anemia or gastrectomy, achlorhydria, malabsorption or lack of integrity of the terminal ileum. There is abundant accumulated evidence that the replacement of B12 can be carried out effectively orally. ![]() This treatment does not usually produce adverse effects, but it involves repeated visits, discomforts and risks in relation to the use of the parenteral route. The most usual regimen consists of daily doses of 1,000 μg for one week, followed by weekly injections for 4 weeks and, then, monthly. The administration of vitamin B12 to correct or prevent the deficiency is usually for life, and has traditionally been prescribed in the form of intramuscular injections. Vitamin B12 passes into the bloodstream bound to transcobalamin II, which transports it to the liver and other areas of the body. The B12-FI complex binds to the ileal cell receptors and is absorbed by endocytosis. It is absorbed in the distal ileum, after passing through the small intestine linked to the intrinsic factor (IF), a protein synthesized in the parietal cells of the gastric fundus. The vitamin ingested in the diet is separated from animal proteins by pepsin and gastric hydrochloric acid, joining haptocorrin, a protein of salivary origin, which is dissociated in the duodenum by the action of pancreatic proteases. ![]() The human organism is not able to synthesize it and must obtain it from the diet, mainly from foods of animal origin (meat, milk and derivatives, eggs, fish). Vitamin B12 or cobalamin plays a key role as a coenzyme in DNA synthesis and cell maturation, as well as in the synthesis of neuronal lipids. The daily dose of 1 mg (1000 mcg) oral cobalamin has shown good long-term results the possibility of intermittent maintenance guidelines is investigated. Is It OK To Take 1000 mcg of Vitamin B12 a Day? ![]()
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![]() You can still choose to enable or disable the select filler function with the Segment Tool from the Timeline Settings. Or maybe the question is, how many steps do you need to take to choose the filler or blank space in your timeline? To select filler or not select filler… that is the question. Select Filler with Segment Tools faster with a simple keystroke This improved design not only makes enablers easier to toggle, but it also eliminates spacing issues with other interface elements. In this latest release, all “enablers,” which are used to toggle a clip’s or track’s parameters on or off, have been updated with a new overall appearance and consistent size in the Effect Editor, Color Correction toolset, and Avid Titler+ mini menu. ![]() We constantly make updates to improve the editor experience within Media Composer. With Media Composer 2022.7, you can step into your nested effects and add timeline clip notes that will be seen on the nested clips. Display timeline clip notes for nested clipsĬreating multilayered effects within a clip in your sequence can produce some amazing results, but there may be a specific note that needs to be added to the nested effect or layer to communicate a comment or note. If you prefer to have a different anchor point than what is set by default, you can manually move the anchor point to a desired position to set the text box or shape layer for rotation. ![]() When toggling between justifications (left, center, right), the text will shift accordingly around this same anchor point. If your text justification is set to “Horizontal Justify Left,” the anchor point will be positioned at the bottom-left corner of the layer (as denoted by the bounding box). This anchor point is set according to the justification of the text by default. When creating titles, you will now see an anchor point on each text box and shape you add. Justify text relative to an anchor point in Avid Titler+Īlong with providing better performance and control, we’ve made improvements to the Avid Titler+ tool. This feature is highly customizable with Media Composer running, you can choose the preferred behaviour when switching between configurations and save it as an Interface setting. You can either update to a workspace matching the current configuration or continue running with the same workspace. Upon launch, Media Composer detects the updated monitor configuration. This gives you the ability to create more than one predefined workspace (Edit, Effects, Color, and Audio), as well as custom workspaces with the monitor configuration embedded, so you can start working right away when changing monitor configurations instead of having to manually rearrange your interface layout each time. With Media Composer 2022.7, the software will now recognize the monitor count and configuration in use and embed the parameters within the Workspace settings. If you change the configuration of your displays, you want your workspaces to remember the position of your windows and tools. Maybe your workstation is set up with a single display-especially if you’re working on a laptop-and you may have two or three displays you can connect to, providing a large set of real estate for your bins and toolsets. And more! Create custom workspaces for multiple monitor configurationsĬustomizing your Media Composer Workspaces is a great way to create a user experience designed the way that you like to lay out your interface. Get comfy with familiar keyboard mapping from Adobe Premiere or DaVinci Resolve when transitioning. Communicate clip notes more visibly in your timeline. With new enhancements in Media Composer 2022.7, you can create custom workspaces when working with different monitor configurations, and Media Composer will automatically remember your interface layout based on your display configuration. Or gain real-time collaboration, MediaCentral integration, and additional dialog search, finishing, and newsroom tools with Media Composer | Ultimate. Access the full suite of industry-standard editing tools with the new low-cost Media Composer, starting at only $19.99 USD/month. Get started for free with Media Composer | First. ![]() Got a story to tell? There’s a Media Composer for everyone.
![]() ![]() Return to Castle Wolfenstein is a reboot of the original Wolfenstein 3D first-person shooter which was released for MS-DOS and other computer systems in the early 1990s. The core game and its expansion packs have been re-released in a number of combo packs. The second expansion called Breakthrough moves the game to the North African campaign, Sicily, and Italy depicting famous battles such as the Battle of Kasserine Pass, The Battle of Monte Cassino and more. ![]() Medal of Honor Allied Assault also had two expansion packs released, Medal of Honor Allied Assault Spearhead which centers around a paratrooper fighting on D-Day, The Battle of the Bulge and behind enemy lines in Berlin. In it players take on the role of US Army Lt Mike Powell as he fights to survive D-Day and the opening days of the invasion of Europe. Medal of Honor Allied Assault was the third game in the Medal of Honor series but just the first released for the PC following the success of the original Medal of Honor for the Sony PlayStation system. Medal of Honor: Allied Assault, was released back in 2002, right in the middle of that "golden age" of World War II shooters that saw the release of numerous World War II-themed games that are part of this list. Theater of Operations: European Playable Factions/Nations: USA, Germany (multiplayer only) Both the core game and expansion pack can be found bundled in the Deluxe Edition or through many digital distributors. ![]() In addition to the core Call of Duty game, there was also one expansion pack called Call of Duty: United Offensive. While it may no longer have the most state of the art graphics, the gameplay and storyline are still top rate and it is a nostalgic look back at the game that started one of the most successful video game franchise in history.Ĭall of Duty features three single-player storylines and six competitive multiplayer modes. After nearly a dozen years since its release, it is still the standard bearer when it comes to Top World War II shooters. The original Call of Duty released back in 2003 tops the list of best World War II first-person shooters. Playable Factions/Nations: USA, UK, USSR, Germany (multiplayer only) ![]() ![]() ![]() 4 Pedro Alonso (48, Assumed Married) Pedro Alonso was born on the 221st of June, 1971 in Vigo, Pontevedra, Galicia, Spain. Yes it is real and we are absolutely happy to announce an off on 3rd September naming it to be "Netflix & Chill Holiday" on the release of final season of #MoneyHeist Please don't end this one! "Kehdo Ye Juth Hai" pic.twitter. He will have time to focus on other things once his career is well established. Have Been Going Over the Love We have Received.! He took to social media to announce this news and said, "It is okay to take a break every once in a while." To carry out the biggest heist in history, a mysterious man called The Professor recruits a band of eight robbers who have a single characteristic: none of them has anything to lose. The CEO of the firm, Abhishek Jain, seeing the online craze and love for the show as a chance to thank his employees for their hard work during the COVID-19 pandemic. Money Heist season 5 cast: who is returning to the gang In season four, crucial gang member Nairobi died but that doesn’t mean Alba Flores won’t be part of the next season. A company named 'Verve Logic' has declared a holiday on September 3, announcing it as 'Netflix and Chill Holiday' as the show releases on the same day. Helsinki (Mirko Dragic) Netflix In the first heist. Check out to know the other cast & crew details, release date, episodes, review. She would be higher on the list if we didnt dislike her so much during the first heist for trying to trap The Professor and his crew. ![]() Check out to know the other cast & crew details, release date, episodes, review. Money Heist Season 2: which is an Antena 3 exclusive features Úrsula Corberó and Itziar Ituño in lead roles. ‘Money Heist 5’ has created a buzz across the world with its latest season as fans are planning a special screening, online watch parties (yes, it's still a thing) and what not but this particular Jaipur-based firm has made its employees super happy with an unexpected gift from their CEO. Money Heist Season 3: which is an Antena 3 exclusive features Úrsula Corberó and Álvaro Morte in lead roles. ![]() ![]() ![]() ![]() In Premiere Pro, use the Select In to Out command to select clips based on In and Out points on targeted tracks. These keyboard driven commands must be set in the Keyboard Shortcuts dialog box prior to using them. In Premiere Pro, use the Select Next Clip or Select Previous Clip commands to select clips on targeted tracks at the current location of the playhead. To select clips in a track independently of its linked video or audio, Alt-click (Windows) or Option-click (Mac OS) using the Track Select tool. To select all clips that exist on and after a certain time on one track, simply shift-click with the Selection tool, then release the Shift key to drag.Shift-dragging a marquee that includes selected clips deselects them. Shift-dragging a marquee that includes deselected clips adds them to the current selection. To add or subtract a range of clips in the current selection, Shift-drag a marquee around clips.To select a range of clips, click in an empty area of the sequence under the time ruler, and then drag a rectangle (marquee selection) that includes any part of the clips you want to select. (Shift-click a selected clip to deselect it.) To select multiple clips by clicking, use the Selection tool and Shift-click each clip you want to select. To select only the audio or video portion of a clip, use the Selection tool and Alt-click (Windows) or Option-click (Mac OS) that portion. To select a single clip, use the Selection tool and click a clip in a Timeline panel. Using the Source Monitor and Program Monitor.Troubleshoot issues related to playback and performance in Premiere Pro.How do I manage the Media Cache in Premiere Pro?.Green and pink video in Premiere Pro or Premiere Rush.Check if your system is compatible with Premiere Pro.Improving Performance and Troubleshooting.Best Practices: Working with native formats.Best Practices: Learning from broadcast production.Consolidate, transcode, and archive projects.Archive, restore, or delete Team Projects.Share and manage changes with Team Project collaborators.Best Practices: Working with Productions.How clips work across projects in a Production.Use Frame.io with Premiere Pro and After Effects.Collaboration: Frame.io, Productions, and Team Projects.Exporting projects for other applications.Exporting for the Web and mobile devices.Using HSL Secondary controls in the Lumetri Color panel.Adjust color using RGB and Hue Saturation Curves.Get creative with color using Lumetri looks.Overview: Color workflows in Premiere Pro.Compositing, alpha channels, and adjusting clip opacity.Viewing and adjusting effects and keyframes.Use Motion effect to edit and animate clips.Adding, navigating, and setting keyframes.Upgrade Legacy titles to Source Graphics.Retiring the Legacy Titler in Premiere Pro | FAQ.Best Practices: Faster graphics workflows.Use data-driven Motion Graphics templates.Replace images or videos in Motion Graphics templates.Install and use Motion Graphics templates.Add Responsive Design features to your graphics.Change the appearance of text and shapes.Overview of the Essential Graphics panel.Automatically reframe video for different social media channels.Overview of video effects and transitions.Set up and use Head Mounted Display for immersive video in Premiere Pro. ![]()
![]() ![]() Though improved fitness may prove true in the Jingwei et al. Harmful phenotypes brought about by chimeric proteins After further studies accomplished by Long M et al., it was concluded that this amalgamation of different protein domains resulted in a more favored selection. This new-fangled gene acts on long-chain alcohols and diols, such as pheromones and hormones, resulting in a direct change in the Drosophila’s fitness (ability to foster viable fertile offspring). The chimeric protein that resulted from these genes was derived from a gene that codes for alcohol dehydrogenase, and the yellow emperor gene. ![]() In contrast, some chimeric genes may result from errors in DNA replication or repair.įor example, one peptide chain might have varying properties which could contribute to binding, recognition, or even toxicity, while its fused counterpart could aid in the targeting and stabilizing of the chimeric polypeptide.Īn example of a chimeric gene, brought about by the joining of two or more genes that initially coded for separate proteins, are the Jingwei genes found in Drosophila. One is artificial, through two or more predetermined coding sequences. These chimeric genes can originate in two different ways. These fabricated chimeric genes often take the form of a plasmid or virus, an effective hull for gene manipulation. The genes will then be transcribed from the DNA, resulting in mature mRNA that will then be translated into a cohesive polypeptide chain, forming our chimeric protein in question. To code for chimeric proteins, one must first construct the chimeric genes. Creating chimeric genes and chimeric proteins In creating these expression vectors the target of regulation is often transcription. With this genetic manipulation to create chimeric proteins, we can control the activity of many specified proteins, providing new insights into the field of therapeutics. Site-directed mutagenesis performed with certain expression vectors can allow for these gene fusions. Translation of these chimeric genes generates a single polypeptide chain, expressing different functionality from the original proteins from which it was derived. Simply put, these chimeric proteins are a result of the fusion of chimeric genes through structural machinery (RNAs, rRNAs, tRNAs). By Vasco Medeiros, BSc Reviewed by Emily Henderson, B.Sc.Ĭhimeric proteins are fashioned through in vitro methodologies. ![]() ![]() ![]() It’s just a shame that the same attention isn’t paid to the other members of the team in this regard.Ĭall of Duty’s moment-to-moment gameplay is still primarily a well-dressed shooting gallery, but Black Ops Cold War succeeds in making its quiet time a defining part of its experience rather than just a deep breath between the loud and explode-y sequences. ![]() Its story is less successful at leaving a Black Ops 1-level mark, but the importance placed on finding and deciphering evidence as well as the multiple endings give good reason to stick with it beyond its typical six-ish-hour runtime. Read the full Call of Duty Black Ops Cold War Single-Player Campaign ReviewĮach of the four heroes possesses their own perks, such as Jackson being able to highlight enemies through smoke and foliage and slowing down time to execute them Red Dead-style. Call of duty black ops 4 background full# But none feels quite as fun or fluid as Petrova’s added movement capabilities. It kind of just made me wish that I was playing as her the whole time, rather than switching back to her less interesting comrades. Call of duty black ops 4 background series#Įspecially when all the best missions are hers.Īll in all, though, there’s just not the variety in mission design that we’ve come to expect from a Call of Duty campaign, especially when compared to the heights that both the Modern Warfare and Black Ops series have reached. You’ll have boots on the ground running from objective marker to objective marker for the vast majority of Vanguard’s brief five-hour runtime. Call of duty black ops 4 background series#.Call of duty black ops 4 background full#. ![]() ![]() ![]() There’s a lot of overlap there, but they each have their own melodies. In many ways, it’s like, ‘Is that Galadriel’s theme?’ because she is out to get him. “He affects people in ways that are really cool. It’s like an illness in your mind,” McCreary shared. “I describe it like the beehive in your mind. The Dark Lord’s haunting theme is employed throughout the series, even when characters are only talking about him. Sauron’s dark energy looms over Middle-earth in the show, so the TV composer used string instruments to create a sense of urgency. “Every second of the show has a thought put into what language will be there,” he noted. McCreary also wrote a theme for the show’s Big Bad, Sauron, containing “this very ominous melody” that is sung in Black Speech (the language used in Sauron’s realm Mordor). “It has a little more of a Celtic vibe, because she’s our Frodo in a way, but I wanted to create something different.” ![]() “The theme I wrote for Nori, in particular, has more Howard Shore vibes,” he continued. He’s visited Middle-earth for six movies now, and. It would just be wildly inappropriate and in the wrong story.” Howard Shore’s iconic score for Peter Jackson’s The Lord of the Rings trilogy is regarded as one of the greatest soundtracks ever produced. That sets it apart from the British folk music heard throughout Lord of the Rings, which “really takes us to a kind of Tolkienien color, which is an 18th century ideal the homes the farmhouses. He went for an earthy vibe with the Harfoots, focusing on the idea that they’d turn a log they found in the forest into a musical instrument. So for me, I wanted to draw that influence from British and Celtic folk music that Howard Shore used, but I also wanted something that was more nomadic that took me to another place, and I used West African percussion.” “There is no Shire when we open on our show. It’s nostalgia for a very specific place, and that’s not what our show is about,” McCreary explained. “In my mind, the theme that wrote is the Shire theme. (Shore did, however, compose the main theme for Rings of Power.) McCreary, who wrote the music for all eight Season 1 episodes, worked to create a distinct sound that was influenced by Shore but didn’t feel like a rehash of what came before - especially when it came to the Hobbit ancestors, the Harfoots. The show is in no way connected to Peter Jackson’s Lord of the Rings trilogy, which featured an iconic score by Howard Shore. ![]() The actors, the editors, and me… It’s going to surprise fans in a pleasant way. The person writing is definitely the right person. “I get it,” he adds, “but the person doing the costumes is the right person. ![]() ![]() Personally, weekly and bi-weekly is not an option I like – it’s too often and it doesn’t give a proper overview of expenses. My best tip would be to try it all and see what works. Different things work for different people. Which format should you choose? I don’t know. There are tons of options for you to monitor your finances: The same goes for financial spreads and trackers. ![]() The thing is – your Bullet journal is versatile and you can use it however you want. With the help of these questions you’ve probably already figured out what’s up and where you need help, so let’s get into different financial Bullet Journal page ideas to help you. What are some money habits I need to get rid of?.What habits do I want to develop when it comes to money management? (like a habit of tracking your expenses can absolutely do wonders for you!).How do people I admire manage their money? (here I probably mean people whose financial management you admire, rather than just their personality.What are my current financial struggles?.I have complete control over my stationery shopping.īut back to our analysis, here are a few questions you might want to ask yourself: But that’s ok – just be honest with yourself! It can be pretty scary to admit that, for example, you didn’t really need those 2 new sets of Tombow that were on sale and could’ve instead saved that money. Get a cup of tea and your comfy blanket, grab your pen and journal and brainstorm a bit about where you’re at with your finances and what you need help with. To develop a financial system that works for you, you have to first ask yourself some tough questions. Thank you for supporting Masha Plans! Discover Where You’re At Please see my Disclosure for more details. They will be of no extra expense for you, but I receive a small credit. ![]() With just minimal effort, you’ll discover that you can save and afford many more things.īefore we get into Bullet Journal pages to help you make it work, let’s look at your financial situation. If you’re in the USA – paying off stuff on time will help you get a better credit score and that of course leads to tons of awesome perks.īy managing your finances, you’ll also be able to save up more for your dream house or maybe that amazing 5-star luxury vacation. Keeping an eye on your finances can help you so much!įirst of all, it will help you to be better at paying your bills and covering up your debt. Of course, when you sit down to get organized the first time it might take a while, but once you have your system cracked – it will be easy as pie! (now I want some pie…) Keeping up with money sounds like a very daunting, scary, and boring chore, but believe me, it’s not as bad as it sounds. So here we are I’ll be sharing with you all the ideas to bring financial planning to your Bullet Journal and will start doing the same myself! I’ve been doing my finances mostly on Google sheets, but the deeper I went into a hole of money management, the more I realized how much better it would be to actually use my Bullet Journal. Be sure to follow me on Instagram for more tips and tricks.Today we will finally tackle finances and what Bullet Journal page ideas can help you organize your money.įor someone like me, who definitely has a shopping addiction, especially if we are talking about stationery shopping, financial spreads are a must-have. ![]() Whether you start tracking your expenses using your Bullet Journal or another way, I would suggest you do it! It is super eye-opening and it has made me feel more in control of my finances. For the moment thought I want to be able to see where my money is going. Over the next few months I will create a budget and track my bills. This is to make sure I use it and so that it is easy to follow. My expense tracker spread for April.Īs you can see from the video I have kept my expense tracker simple. Watch my video below to see how you can re-create my spread at home. ![]() The theme in my travel bullet journal this month is Japan. I use my bullet journal every day now, it is the perfect place for me to track my finances. In the past, I have used notebooks or apps, neither have worked for me. my bullet journal expense tracker.įor the month of April, I have created an expense tracker for the first time in my bullet journal. This means that your expense tracker isn’t weighed down with things you have to pay for every mont. Of bills, it can be easier to have a separate bills tracker for things like rent. ![]() ![]() I'm not sure if the curved black background is a person's shoulder or not. You can see a knife blade handle jutting in from the left. In order for you to see it better I played with the lighting in Photoshop.Īnd in this I isolated the skull and straightened it up. You can see more of his work and purchase photos there. This is the address for Billy Name's website:. The skull was found on early printings of the album cover. The skull was photographed by Billy Name, a photographer associated with the Warhol factory. ![]() Here's another view of the skull, from an album on Ebay. But if you saw the cover lit at a certain angle, you could see that there was a photo of a pirate-like tattoo printed on the cover in black ink. This is the front cover of the Velvet Underground's second album: White Light/White Heat. ( see or purchase their photos at and )Īnd here is shot of the right inner sleeve of the album.Īlbum Title: White Light, White Heat, Verve Records, 1968 The liner photos are by Nat Finkelstein and Billy Name. This is s shot of the left inner sleeve of the album. A legal dispute as to the use of the man's image led to the record company covering that part of the picture in later printings of the cover. If you look in back of Lou Reed's head there is a larger picture of a man's head. ![]() I am not sure of which venue the photo were taken (but check back). This is a photo of the back cover of "the banana" album. (Later, Warhol would produce a similar cover for Sticky Fingers by the Rolling Stones containing a 3-d zipper that could be unzipped to reveal a waist-view of man wearing white underpants. In the original first pressing of the album, under the words "PEEL SLOWLY AND SEE": one could peel off the the bright yellow banana sticker to reveal a pink ( almost flesh colored (get it?)) banana inside.Ī year after the album's release, when it began too take too much time to hand attach the stickers, the sticker was replaced by a photograph. This is the front cover of the Velvet Underground's first album. To be notified of new PopSpots entries, follow PopSpotsNYC on Twitter:įor questions or comments you can email me (Bob)Īlbum: THE VELVET UNDERGROUND & NICO, Verve Records, 1967 ![]() |
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